Russian Journal of General Chemistry

Formation, structure and heterocyclization of aminoguanidine and ethyl acetoacetate condensation products

AV Erkin, VI Krutikov

Index: Erkin; Krutikov Russian Journal of General Chemistry, 2009 , vol. 79, # 6 p. 1204 - 1209

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Citation Number: 3

Abstract

Abstract Condensation of aminoguanidine hydrochloride and ethyl acetoacetate results in 2, 3-diamino-6-methylpyrimidin-4 (3 H)-one, 5-hydroxy-1-carboxamidino-3-methylpyrazole or ethyl N-[(5-hydroxy-3-methylpyrazol-1-yl) imidoyl] aminocrotonoate depending on the type of the base. Formation of pyrazole derivatives occurs in the case of dequaternized substrate imine-group protonating by the acids formed as a result of ion exchange reaction. Chelate ...