Synthesis and Evaluation of α??Methylidene?螃摸?butyrolactone bearing flavone and xanthone moieties

CC Tzeng, YL Zhao, YL Chen, SS Liou…

Index: Tzeng; Zhao; Chen Helvetica Chimica Acta, 1997 , vol. 80, # 8 p. 2337 - 2344

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Citation Number: 12

Abstract

Abstract In a search for inhibitors of platelet aggregation, a number of α-methylidene-γ- butyrolactones 5 and 6 bearing flavone or xanthone moieties, respectively, were synthesized and evaluated for their antiplatelet activity against thrombin (Thr)-, arachidonic-