Sur les enolates lithies de cetones. Cetolisation mixte univoque et regiospecifique

F Gaudemar-bardone, M Gaudemar

Index: Gaudemar-Bardone,F.; Gaudemar,M. Journal of Organometallic Chemistry, 1976 , vol. 104, p. 281 - 292

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Citation Number: 13

Abstract

Abstract The deprotonation around− 70 C of the ketones RCH 2 COCH 3 or R 2 CHCOCH 3 by Et 2 NLi in the mixture HMPT/benzene/ether gives the enolates RCH 2 C (OLi) CH 2 or R 2 CHC (OLi) CH 2. The condensation of the latter with different aldehydes or ketones around− 70 C lead to the expected β-ketols Full-size image (1 K)