Synthetic Communications®

Simple and Efficient Synthesis of 3-(N-Hydroxylamino)-1, 3-diarylpropan-1-one Oximes Under Ultrasound Irradiation

JT Li, XH Zhang, ZP Lin

Index: Li, Ji-Tai; Zhang, Xiao-Hui; Lin, Zhi-Ping Synthetic Communications, 2008 , vol. 38, # 16 p. 2838 - 2844

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Abstract

In 1998, Powers et al. first studied the reaction of chalcone with hydroxylamine hydrochloride under basic conditions to form the isoxazoline ring system by heating at 80 °C for 12 h. Chalcones were chosen as the featured building block because of their chemical flexibility toward further