Efficient synthesis of 2, 4-disubstituted quinolines: calix [n] arene-catalyzed Povarov-hydrogen-transfer reaction cascade

JB Simões, Â de Fátima, AA Sabino, LCA Barbosa…

Index: Simoes, Juliana Baptista; De Fatima, Angelo; Sabino, Adao Aparecido; Almeida Barbosa, Luiz Claudio; Fernandes, Sergio Antonio RSC Advances, 2014 , vol. 4, # 36 p. 18612 - 18615

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Citation Number: 11

Abstract

Another important factor in the Povarov reaction is the catalyst employed. In recent years, our group and others have initiated the use of calix[n]arenes as catalysts in certain selective reactions, 17 including a Povarov reaction designed for the synthesis of julolidines. 18 Taking advantage of calix[n]arenes as catalysts, we report an unprecedented tandem multicomponent synthesis of 2,4-disubstituted quinoline derivatives via a Povarov reaction in this study. As ...