Silicon-directed selective gamma substitution of an α, β-unsaturated ester
P Albaugh-Robertson, JA Katzenellenbogen
Index: Albaugh-Robertson, Pamela; Katzenellenbogen, John A. Tetrahedron Letters, 1982 , vol. 23, # 7 p. 723 - 726
Full Text: HTML
Citation Number: 26
Abstract
Abstract Ethyl 3-methyl-2-trimethylsilyl-3-butenoate (3) undergoes reaction selectively at carbon 4, upon treatment with a Lewis acid and carbonyl compounds, acetals/ketals, acid chlorides, and chloromethyl phenyl sulfide. This overall conversion represents a highly selective gamma substitution on an α, β-unsaturated ester.
Related Articles:
Palladium-Catalyzed Carbonylative Couplings of Vinylogous Enolates: Application to Statin Structures
[Yamamoto, Yoshiri; Hatsuya, Satoshi; Yamada, Jun-ichi Journal of the Chemical Society, Chemical Communications, 1988 , # 2 p. 86 - 87]
Palladium-Catalyzed Carbonylative Couplings of Vinylogous Enolates: Application to Statin Structures
[Yamamoto, Yoshiri; Hatsuya, Satoshi; Yamada, Jun-ichi Journal of the Chemical Society, Chemical Communications, 1988 , # 2 p. 86 - 87]