A novel synthesis of purine and deazapurine derivatives from 5-aminoimidazoles
AH Al-Shaar, DW Gilmour, DJ Lythgoe…
Index: Al-Shaar, Adnan H.; Gilmour, David J.; McClenaghan, Ian; Ramsden, Christopher A. Journal of the Chemical Society, Chemical Communications, 1989 , # 9 p. 551 - 552
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Abstract
A Novel Synthesis of Purine and Deazapurine Derivatives from 5-Aminoimidazoles ... Adnan H. Al-Shaar, David W. Gilmour, David J. Lythgoe, Ian McClenaghan, and Christopher A. Ramsden* Dagenham Research Centre, Rhbne-Poulenc Ltd., Dagenham, Essex RM I0 7XS, UK ... Catalytic reduction of 4-unsubstituted-5-nitroimidazoles (3) in 1,4-dioxane solution is an excellent route to the 5-aminoimidazoles (1) which can be isolated or used in situ to ...
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