Gold Catalysis: Non??Spirocyclic Intermediates in the Conversion of Furanynes by the Formal Insertion of an Alkyne into an Aryl–Alkyl C C Single Bond

…, S Pankajakshan, S Schäfer, L Schultes…

Index: Hashmi, A. Stephen K.; Haeffner, Tobias; Yang, Weibo; Pankajakshan, Sreekumar; Schaefer, Sascha; Schultes, Lara; Rominger, Frank; Frey, Wolfgang Chemistry - A European Journal, 2012 , vol. 18, # 34 p. 10480 - 10486

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Citation Number: 28

Abstract

The gold-catalyzed transformation of furanynes 1 [1] represents one of the first homogeneous gold-catalyzed conversions with a broad scope; it was only preceded by the Ito–Sawamura–Hayashi asymmetric aldol reaction [2] and the nucleophilic addition reactions that form new CÀN and CÀO bonds.[3] The substrates 1 possess a 1, 6-enyne substructure and, for terminal alkynes, are reliably converted to I (Scheme 1). During the ...

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