Nature of the Intermediates in Gold (I)??Catalyzed Cyclizations of 1, 5??Enynes

V López??Carrillo, N Huguet, Á Mosquera…

Index: Lopez-Carrillo, Veronica; Huguet, Nuria; Mosquera, Ungeles; Echavarren, Antonio M. Chemistry - A European Journal, 2011 , vol. 17, # 39 p. 10972 - 10978

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Citation Number: 52

Abstract

Abstract The carbene or carbocationic nature of the intermediates in the gold-catalyzed cycloisomerization of 1, 5-enynes can be revealed, depending on the ligands on the gold catalysts. Gold complexes with highly electron-donating ligands promote reactions that proceed via intermediates with carbene-like character, leading to products with a bicyclo [3.1. 0] hexene skeleton. The intermediate cyclopropyl endo-gold carbenes formed in this ...