Antibacterial effects of poly (2-(dimethylamino ethyl) methacrylate) against selected gram-positive and gram-negative bacteria

…, G Mantovani, JA Syrett, DM Haddleton…

Index: Rawlinson, Lee-Anne B.; Ryan, Sinead M.; Mantovani, Giuseppe; Syrett, Jay A.; Haddleton, David M.; Brayden, David J. Biomacromolecules, 2010 , vol. 11, # 2 p. 443 - 453

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Citation Number: 85

Abstract

Antimicrobial coatings can reduce the occurrence of medical device-related bacterial infections. Poly (2-(dimethylamino ethyl) methacrylate)(pDMAEMA) is one such polymer that is being researched in this regard. The aims of this study were to (1) elucidate pDMAEMA's antimicrobial activity against a range of Gram-positive and Gram-negative bacteria and (2) to investigate its antimicrobial mode of action. The methods used include determination of ...