Ruthenium-catalyzed cyclic carbonylation of allenyl alcohols. Selective synthesis of γ-and δ-lactones

…, T Kaneko, SW Zhang, K Onitsuka, S Takahashi

Index: Yoneda, Eiji; Kaneko, Takayuki; Zhang, Shi-Wei; Onitsuka, Kiyotaka; Takahashi, Shigetoshi Organic Letters, 2000 , vol. 2, # 4 p. 441 - 443

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Citation Number: 94

Abstract

Ruthenium complex-catalyzed carbonylation of allenyl alcohols quantitatively gave cyclic carbonyl compounds, γ-and δ-lactones, in which the hydroxy group of allenyl alcohols participated in the cyclization. A wide variety of allenyl alcohols, such as mono-, di-, and trisubstituted alcohols, can be used in this reaction to produce 3-and 4-substituted γ- lactones. Similarly, the cyclic carbonylation of 3, 4-pentadien-1-ol 10a and 2-methyl-4, 5- ...