Synthesis and Evaluation of Antibacterial Activities of 5, 7??Dihydroxycoumarin Derivatives

YP Chin, WJ Huang, FL Hsu, YL Lin…

Index: Chin, Yi-Ping; Huang, Wei-Jan; Hsu, Feng-Lin; Lin, Mei-Hsiang; Lin, Yuh-Ling Archiv der Pharmazie, 2011 , vol. 344, # 6 p. 386 - 393

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Citation Number: 8

Abstract

Abstract This study examines the synthesis and antibacterial activities of 5, 7- dihydroxycoumarin derivatives, whose structures were confirmed using analytical and spectral data. Twenty compounds were tested for their antibacterial activities against five microbial species such as E. coli, S. aureus, K. pneumonia, P. aeruginosa, and S. typhimurium were studied. Compounds 5 and 12 exhibited the most potent activity against ...