Michael Additions in Aqueous Media:“On??Water” and “In??Water” Processes from α??Nitro Ketones and Their Anions

G Giorgi, P López??Alvarado, S Miranda…

Index: Giorgi, Giorgio; Lopez-Alvarado, Pilar; Miranda, Sonia; Rodriguez, Jean; Menendez, J. Carlos European Journal of Organic Chemistry, 2013 , # 7 p. 1327 - 1336

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Citation Number: 9

Abstract

Abstract A variety of α, β-unsaturated aldehydes and ketones gave very high-yielding Michael addition reactions with α-nitrocycloalkanones in water, at room temperature without added catalyst. These can be considered as one of the very few “on-water” Michael reactions known in the literature, because they took place in suspension or emulsion and at increased speed relative to the same transformations performed in organic solvents. A ...