Molecular recognition of the antiretroviral drug abacavir: towards the development of a novel carbazole-based fluorosensor

…, PJ Cywinski, CG Cranfield, GJ Mohr, R Beckert

Index: Idzik, Krzysztof Ryszard; Cywinski, Piotr J.; Cranfield, Charles G.; Mohr, Gerhard J.; Beckert, Rainer Journal of Fluorescence, 2011 , vol. 21, # 3 p. 1195 - 1204

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Citation Number: 2

Abstract

Abstract Due to their optical and electro-conductive attributes, carbazole derivatives are interesting materials for a large range of biosensor applications. In this study, we present the synthesis routes and fluorescence evaluation of newly designed carbazole fluorosensors that, by modification with uracil, have a special affinity for antiretroviral drugs via either Watson–Crick or Hoogsteen base pairing. To an N-octylcarbazole-uracil compound, four ...