Novel synthesis of chromene and benzofuran derivatives via the Nenitzescu reaction

…, LM Alekseeva, SA Savina, AS Shashkov…

Index: Lyubchanskaya, Valeria M.; Alekseeva, Lyudmila M.; Savina, Svetlana A.; Shashkov, Alexander S.; Granik, Vladimir G. Mendeleev Communications, 2002 , vol. 12, # 1 p. 15 - 17

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Citation Number: 2

Abstract

The condensation of 3-oxocaprolactam piperidine enamine with 2, 6-dibromoquinone and quinone gave 6, 8-dibromo-7-hydroxy-and 7-hydroxy-10a-piperidine-2, 3, 4, 5, 5a- hexahydro-1H-benzofuro [2, 3-c] azepine-1-one adducts, the acid treatment of which afforded novel 9-hydroxy-1, 2, 3, 4-tetrahydro-5H-chromene [3, 4-b] pyridine-5-one derivatives.