Tetrahedron letters

Stereoselective synthesis of (25R)-25, 26-dihydroxy-23-oxovitamin D 3 and its enzymatic conversion to (25R)-1α, 25, 26-trihydroxy-23-oxovitamin D 3, a putative …

S Yamada, K Nakayama, H Takayama, T Shinki…

Index: Yamada; Nakayama; Takayama; et al. Tetrahedron Letters, 1984 , vol. 25, # 30 p. 3239 - 3242

Full Text: HTML

Citation Number: 8

Abstract

The Department of Biochemistry, School of Dentistry, Showa University, l-5-8 Hatanodai, Shinagawa-ku, Tokyo 142, Japan Summary:(25l?)-25, 26-Dihydroxy-23-oxovitamin D3 was synthesized efficiently and stereoselectively, and it was converted enzymatically to (25R_)- lcr, 25, 26-trihydroxy-23-oxovitamin D3, a putative metabolite of la, 25_dihydroxyvitamin D3. The spectral and chemical properties of (25R&25, 26-dihydroxy-23-oxovitamin D3 and its ...