Tetrahedron letters

On the stereospecific reduction of vinylsulfoxides with thepossibility of deuterium labeling

PG Theobald, WH Okamura

Index: Theobald, Paula G.; Okamura, William H. Tetrahedron Letters, 1987 , vol. 28, # 52 p. 6565 - 6568

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Citation Number: 16

Abstract

Abstract: Upon treating triene sulfoxide 2 or 3 in the presence of methanol (internal proton source> in ether with tert-butyllithium, the reduced product 4b or 4c, respectively, is obtained with retention of configuration. A deuterium label can be incorporated by using methanol-O- d1 as the internal proton source.