Application of (2-cyanoaryl) arylacetonitriles in cyclization and annulation reactions. Preparation of 3-arylindans, 4-aryl-3, 4-dihydronaphthalenes, 4-arylisoquinolines, …

…, M Begtrup, KP Boegesoe

Index: Sommer, Michael Bech; Begtrup, Mikael; Boegesoe, Klaus Peter Journal of Organic Chemistry, 1990 , vol. 55, # 16 p. 4822 - 4827

Full Text: HTML

Citation Number: 23

Abstract

(2-Cyanoaryl) arylacetonitriles, obtained from o-halogen-substituted cyanoaromatics and arylacetonitriles may be alkylated with methyl chloroacetate. Subsequent abstraction of the proton adjacent to the ester group followed by attack of the anion at the aromatic cyano ...