ChemCatChem

Kinetic Studies on sec??Alcohol Racemization with Dicarbonylchloro (pentabenzylcyclopentadienyl)??and Dicarbonylchloro (pentaphenylcyclopentadienyl) ruthenium …

D Mavrynsky, DY Murzin, R Leino

Index: Mavrynsky, Denys; Murzin, Dmitry Yu.; Leino, Reko ChemCatChem, 2013 , vol. 5, # 8 p. 2436 - 2445

Full Text: HTML

Citation Number: 5

Abstract

Abstract Pentasubstituted cyclopentadienyl complexes of ruthenium R 5 CpRu (CO) 2 Cl (R= Ph, benzyl) form, upon activation with tBuOK, highly active catalysts for racemization of chiral sec-alcohols. In combination with suitable resolving enzymes, such catalyst systems can efficiently be utilized for dynamic kinetic resolution reactions providing chiral alcohols, after hydrolysis of the corresponding acetates, in high yields and high enantiomeric purities. ...