Palladium-catalyzed heteroarylation of 1-(tert-butyldimethylsilyl)-3-indolylzinc chloride. Efficient synthesis of 3-(2-pyridyl) indoles
M Amat, S Hadida, J Bosch
Index: Amat, Mercedes; Hadida, Sabine; Bosch, Joan Tetrahedron Letters, 1994 , vol. 35, # 5 p. 793 - 796
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Citation Number: 41
Abstract
Abstract Palladium-catalyzed coupling of 1-(tert-butyldimethylsilyl)-3-indolylzinc chloride (2) with either π-deficient or π-excedent heteroaryl halides gives 3-arylindoles in good to excellent yields. The method is extensively applied to the preparation of 3-(2-pyridyl) indoles.
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