An efficient route to pentasubstituted phenols
FA Khan, S Choudhury
Index: Khan, Faiz Ahmed; Choudhury, Sumit European Journal of Organic Chemistry, 2006 , # 3 p. 672 - 676
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Citation Number: 7
Abstract
Abstract A simple and convenient three-step protocol for the synthesis of pentasubstituted tribromophenols based on the acid-catalyzed Grob-type fragmentation of the bicyclic ketone precursors 8a–e in high overall yield is described. The bicyclic ketones 8a–e were obtained in two steps starting from the Diels–Alder cycloadducts 5a–e of β-substituted vinyl acetates and tetrabromo-5, 5-dimethoxycyclopentadiene.(© Wiley-VCH Verlag GmbH & Co. KGaA, ...
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