Synthesis

New highly efficient method for the synthesis of tert-alkyl nitroso compounds

SK Quek, IM Lyapkalo, HV Huynh

Index: Quek, Ser Kiang; Lyapkalo, Ilya M.; Huynh, Han Vinh Synthesis, 2006 , # 9 p. 1423 - 1426

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Citation Number: 5

Abstract

Abstract The syntheses of tert-alkyl nitroso compounds RCH 2 CMe 2 N= O from commercially available tert-alkyl amines RCH 2 CMe 2 NH 2 proceed cleanly via the intermediacy of the benzoyl derivatives RCH 2 CMe 2 NHOC (O) Ph and the corresponding hydroxylamines RCH 2 CMe 2 NHOH. Since the intermediates require no purification in the course of the transformations, the overall yields of the isolated crystalline nitroso dimers ( ...