Chemical Communications

A new protocol for the syntheses of (E)-3-benzylidenechroman-4-ones: a simple synthesis of the methyl ether of bonducellin

D Basavaiah, M Bakthadoss

Index: Basavaiah, Deevi; Bakthadoss, Manickam; Pandiaraju, Subramanian Chemical Communications, 1998 , # 16 p. 1639 - 1640

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Citation Number: 84

Abstract

Development of a simple new methodology for the synthesis of (E)-3-benzylidenechroman-4- ones using methyl 3-aryl-3-hydroxy-2-methylenepropanoates, the Baylis–Hillman adducts derived from methyl acrylate, and the application of this methodology for the synthesis of the methyl ether of bonducellin, an important natural product, and 3-(4-methoxybenzylidene)-6- methoxychroman-4-one, an antifungal agent, are described.