Synthesis of Novel Bifunctional Michael Acceptors

L Mediavilla Urbaneja, N Krause

Index: Urbaneja, Laura Mediavilla; Krause, Norbert European Journal of Organic Chemistry, 2004 , # 21 p. 4467 - 4470

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Citation Number: 5

Abstract

Abstract The conjugated dienones 1a, 1c− e, and 1g were synthesized by aldol reaction of cyclohex-2-enones 3 with aldehydes or ketones and subsequent elimination. Whereas the acetone adducts could be converted into the desired products 1a/g by treatment with CeCl 3· 7H 2 O/NaI, the dienones 1c− e were obtained by Appel bromination and dehydrobromination with triethylamine.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 ...