Templated amplification of a naphthalenediimide-based receptor from a donor–acceptor dynamic combinatorial library in water

HY Au-Yeung, P Pengo, GD Pantoş, S Otto…

Index: Au-Yeung, Ho Yu; Pengo, Paolo; Pantos, G. Dan; Otto, Sijbren; Sanders, Jeremy K. M. Chemical Communications, 2009 , # 4 p. 419 - 421

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Citation Number: 25

Abstract

We report a dynamic combinatorial library that, upon binding of an electronically- complementary guest, produces in high yield a tetrameric receptor with flat hydrophobic, electron-deficient surfaces and flexible, water-soluble disulfide-containing linkers; analysis of the dependence of library composition on template concentration gives insight into the binding behaviours of the species involved.