Tetrahedron letters

Multiply bridged acetylenic thiacyclophanes

HE Ensley, S Mahadevan, J Mague

Index: Ensley, Harry E.; Mahadevan, Shivkumar; Mague, Joel Tetrahedron Letters, 1996 , vol. 37, # 35 p. 6255 - 6258

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Citation Number: 7

Abstract

The 4, 17, 30-trithia-[73](1, 3, 5) cyclophane (1) has been prepared by a two-stage, palladium assisted coupling of propargylOTHP with 1, 3, 5-tribromobenzene, followed by sulfide ring closure. The intermediate (8) on deprotection, followed by bromination and reaction with Na2S gives 1 in 58% yield.