Tetrahedron Letters

Studies on the synthesis and biosynthesis of the fungal alkaloid necatorone

J Carstens, MR Heinrich, W Steglich

Index: Carstens, Joern; Heinrich, Markus R.; Steglich, Wolfgang Tetrahedron Letters, 2013 , vol. 54, # 40 p. 5445 - 5447

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Citation Number: 5

Abstract

Abstract An alternative pathway for the biosynthesis of the fungal alkaloid necatorone has been studied using fluorine-labeled 3-(2-carboxyphenylamino)-l-tyrosine. Although no incorporation of this compound could be detected in feeding experiments with young specimens of Lactarius necator, an analogous 3-aminotyrosine derivative could be converted synthetically into the oxopyridoacridine core structure of necatorone. In ...