A New Simple Synthesis of Optically Active Alkylpyridines: Remarks on the Maximum Rotatory Power of (+)-(S)-3-s. Butylpyridine

…, C Botteghi, S Gladiali, F Soccolini

Index: Asara, G.; Botteghi, C.; Gladiali, S.; Soccolini, F. Synthetic Communications, 1983 , vol. 13, # 13 p. 1129 - 1136

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Citation Number: 3

Abstract

Abstract Our interest in the synthesis of optically active alkylpyridines led us to develop several synthetic routes to these products. 1–5 In particular, 2-alkylsuccinaldehyde monoacetals (1), which can be easily prepared without racemization through rhodium- catalyzed hydroformylation of α, β-unsaturated aldehyde acetals, 6 proved to be valuable starting materials for the preparation of optically active 3-alkylpyridines (6). 2