Journal of the American Chemical Society

The Decarboxylation of Pyrazinium Betaine Salts1

EV Hort, PE Spoerri

Index: Hort; Spoerri Journal of the American Chemical Society, 1955 , vol. 77, p. 5898

Full Text: HTML

Citation Number: 3

Abstract

In the course of a study on the quaternization of 2, 5-dimethylpyrazine (DMP), the reaction with CY-haloacids was found to proceed in an unusual manner. The expected betaine salts could not be isolated. Even at room temperature, carbon dioxide was evolved and only decarboxylated quaternary salts obtained. This ease of decarboxylation contrasts sharply with the stability normally exhibited by betaine salts. For example, l- ...