Tetrahedron letters

Total synthesis of O-methylpallidinine

JE McMurry, V Farina

Index: McMurry, John E.; Farina, Vittorio Tetrahedron Letters, 1983 , vol. 24, # 43 p. 4653 - 4656

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Citation Number: 7

Abstract

Abstract O-Methylpallidinine, a recently isolated morphinan alkaloid, has been synthesized in 16 steps from 1, 4-cyclohexanedione and 3-bromoveratrole. The synthesis employs a new method for preparing the morphinan skeleton in which diazomethane is added to an aryloctahydroquinolinium salt.

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