Polymer supported magnesium anthracene: application in the synthesis of benzylic Grignard reagents

TR van der Ancker, S Harvey, CL Raston

Index: Ancker, Tania R. van den; Harvey, Steven; Raston, Colin L. Journal of Organometallic Chemistry, 1995 , vol. 502, # 1-2 p. 35 - 46

Full Text: HTML

Citation Number: 19

Abstract

Reactions of polystyrene supported magnesium anthracene containing radical anion and dianion sites, 7, 7′, with benzylic chlorides or bromides, affords Grignard reagents, RMgX, in modest to high yields, in THF at− 10° C to 20° C. Novel benzylic-type Grignard reagents prepared in high yield include those of 2, 6-(dichloromethyl) pyridine, 2, 6-(dibromomethyl) pyridine, 2, 2′ 2 ″-trispyridylmethylchloride, 2-methoxy-3-methyl-1-benzychloride, 2, 4- ...