Isolation and characterization of a new 5-aminofurylthiazole from the catalytic reduction of 4-(5-nitro-2-furyl) thiazole.

…, S Swaminathan, E Erturk, GT Bryan

Index: Ichikawa; Fujioka; Hibino; Swaminathan; Erturk; Bryan Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 12 p. 5581 - 5584

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Abstract

As a new extension of catalytic hydrogenation of 4-(5-nitro-2-furyl) thiazole, a convenient procedure for the synthesis of 4-(5-amino-2-furyl) thiazole has been developed using tetrahydrofuran and n-heptane to isolate enough 5-amino compound to determine the