Journal of the Chemical Society, Perkin Transactions 1

… with tetrasulfur tetranitride antimony pentachloride complex (S4N4· SbCl5): complete regioselective formation of 4-substituted 3-acyl-and 3-aroyl-1, 2, 5-thiadiazoles …

KJ Kim, K Kim

Index: Kim, Kil-Joong; Kim, Kyongtae Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 14 p. 2175 - 2180

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Abstract

The reactions of 3-alkyl-5a–f, 3-aryl-5g–m, 3-acylamido-5n, p, 3-benzamido-5o and 3- arylamino-5q-5-alkyl-and-5-aryl-isoxazoles with tetrasulfur tetranitride antimony pentachloride complex (S4N4· SbCl5) in toluene at 90° C to reflux temperature give 3-acyl- 6a–c, e, n–q and 3-aroyl-4-substituted-1, 2, 5-thiadiazoles 6d, f–m in 13 to 61% yields as single isomers. The same reactions of 3, 4-dimethyl-5s, 5v, 4-ethyl-3-methyl-5t-5-alkyl-and ...