β-Elimination of the isonitrile group in alkylation reactions of C–H acids activated by the isonitrile function
M Jawdosiuk, M Umiński
Index: Jawdosiuk, Mikolaj; Uminski, Maciej Journal of the Chemical Society, Chemical Communications, 1982 , # 17 p. 979 - 980
Full Text: HTML
Citation Number: 0
Abstract
During phase-transfer alkylation of the isonitriles R1 R2CHNC with X-CH2-Y, where X is a leaving group and Y an electron withdrawing group, some of the alkylation products undergo p-elimination of the isonitrile function to yield R1 R2C=CHY. ... The phase-transfer technique has been successfully employed for the alkylation of various classes of CH acids1 During our work on phase-transfer alkylation of diphenylmet hyl isocyanide (1) with nitrobenzyl halides we unexpectedly ...
Related Articles:
[Palomo, Claudio; Aizpurua, Jesus M.; Garcia, Jesus M.; Ganboa, Inaki; Cossio, F. P.; et al. Journal of Organic Chemistry, 1990 , vol. 55, # 8 p. 2498 - 2503]
Controlled mono and double Heck reactions in water catalyzed by an oxime-derived palladacycle
[Botella, Luis; Najera, Carmen Tetrahedron Letters, 2004 , vol. 45, # 9 p. 1833 - 1836]
Mono-and β, β-double-Heck reactions of α, β-unsaturated carbonyl compounds in aqueous media
[Botella, Luis; Najera, Carmen Journal of Organic Chemistry, 2005 , vol. 70, # 11 p. 4360 - 4369]
Microwave-assisted copper-catalyzed Heck reaction in PEG solvent
[Declerck, Valerie; Martinez, Jean; Lamaty, Frederic Synlett, 2006 , # 18 p. 3029 - 3032]