Selective RNA Versus DNA G??Quadruplex Targeting by In Situ Click Chemistry

…, R Rodriguez, S Balasubramanian

Index: Di Antonio, Marco; Biffi, Giulia; Mariani, Angelica; Raiber, Eun-Ang; Rodriguez, Raphael; Balasubramanian, Shankar Angewandte Chemie - International Edition, 2012 , vol. 51, # 44 p. 11073 - 11078 Angew. Chem., 2012 , vol. 124, # 44 p. 11235 - 11240,5

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Citation Number: 52

Abstract

Click chemistry has been broadly defined as chemical reactions capable of promoting the formation of stable covalent adducts from two distinct reactive moieties in a mild and quantitative manner with an appreciable tolerance to water.[1] These stringent requirements have rendered the development of click reactions particularly challenging.[2] More recently, the term click chemistry has referred to the 1, 3-dipolar cycloaddition of alkynes and ...