Photocaging strategy for functionalisation of oligonucleotides and its applications for oligonucleotide labelling and cyclisation
M Su, J Wang, XJ Tang
Index: Su, Meng; Wang, Jie; Tang, Xinjing Chemistry - A European Journal, 2012 , vol. 18, # 31 p. 9628 - 9637
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Citation Number: 13
Abstract
Abstract We have used a photocaging strategy to develop novel phosphoramidites and expand the repertoire of protecting groups for modification of oligonucleotides by solid- phase synthesis. We synthesised five photolabile phosphoramidites and four new photolabile controlled pore glasses (CPGs). By using these photolabile phosphoramidites and CPGs, modified oligodeoxynucleotides (ODNs) with phosphate, amine, acid, thiol and ...
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