A directed metalation route to the zwitterionic indole alkaloids. Syntheses of indolo [2, 3-a] quinolizine, flavopereirine, flavocarpine, and dihydroflavopereirine
GW Gribble, DA Johnson
Index: Gribble, Gordon W.; Johnson, David A. Tetrahedron Letters, 1987 , vol. 28, # 44 p. 5259 - 5262
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Citation Number: 42
Abstract
Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... A protocol involving beta-lithiation of 2-(2-pyridinyl)indoles (4 → 5) and subsequent reaction with bromoacetaldehyde or oxirane has led to syntheses of the alkaloids indolo[2,3-a]quinofizine (1), flavopereirine (2), flavocarpine (21), and dihydroflavopereirine (24).
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