Synthesis

Preparation of carboxythiolactones and their active derivatives

BJ Garbiras, S Marburg

Index: Garbiras, Bonnie J.; Marburg, Stephen Synthesis, 1999 , # 2 p. 270 - 274

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Citation Number: 11

Abstract

Abstract: The design of peptidyl immunogens requires that a number of elements be covalently linked to enable the appropriate immune response to occur. Two of these elements are:(a) T-cell sequences which after processing, bind to major histocompatibility complex (MHC) molecules and T-cell receptors and (b) B-cell sequences which embody the constellation of atoms which will ultimately be recognized by the desired antibody. Our ...