Tetrahedron

A convenient and improved preparation of Cyano phosphates

I Micó, C Nájera

Index: Mico, Irene; Najera, Carmen Tetrahedron, 1993 , vol. 49, # 20 p. 4327 - 4332

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Citation Number: 13

Abstract

Introduction Cyanohydrin diethyi phosphates are versatile intermediates in synthetic organic chemistryt specially: (a) in the preparation of satura- and a,&unsaturated 3 nitriles from carbonyl compounds by reductive elimination of the phosphate group, (b) for the regiospecific Friedel-Crafts type arylation of aromatic compounds? (c) in the synthesis of y-hydroxy a$-unsaturated nitriles 4bs and @cyan0 a,fhmahnatd ketones5 by [3,3]-sigmatropic