Tetrahedron Letters

A convenient method for the selective reduction of amides to amines

S Raucher, P Klein

Index: Raucher, Stanley; Klein, Peter Tetrahedron Letters, 1980 , vol. 21, p. 4061 - 4064

Full Text: HTML

Citation Number: 80

Abstract

Abstract A variety of amides have been selectively reduced to the corresponding amines via conversion to their thioamides and treatment with triethyloxonium tetrafluoroborate followed by sodium borohydride. This procedure is compatible with isolated and conjugated double bonds, esters, intro groups, and sulfonamides.