A Facile One??Pot Transformation of Baylis–Hillman Adducts into Unsymmetrical Disubstituted Maleimide and Maleic Anhydride Frameworks: A Facile Synthesis of …

D Basavaiah, B Devendar, K Aravindu…

Index: Basavaiah, Deevi; Devendar, Badugu; Aravindu, Kunche; Veerendhar, Ainelly Chemistry - A European Journal, 2010 , vol. 16, # 7 p. 2031 - 2035

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Citation Number: 24

Abstract

The development of efficient and convenient methodologies for the synthesis of 3, 4- disubstituted maleimide and maleic anhydride derivatives has been, and continues to be, an attractive and challenging endeavor in organic and medicinal chemistry.[1, 2] The importance of these targets is demonstrated by the presence of such frameworks in a number of bioactive natural products, such as himanimides A–D,[1g, i] polycitrins A and B,[ ...