Heteroatom Chemistry

Synthesis and antimicrobial activity of N??substituted N′??[6??methyl??2??oxido??1, 3, 2??dioxaphosphinino (5, 4??b) pyridine??2??yl] ureas

P Reddy, CS Reddy, M Venugopal

Index: Reddy, P. Vasu Govardhana; Reddy, C. Suresh; Venugopal Heteroatom Chemistry, 2003 , vol. 14, # 6 p. 509 - 512

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Citation Number: 7

Abstract

Abstract N-Substituted N′-[6-methyl-2-oxido-1, 3, 2-dioxaphosphinino (5, 4,-b) pyridine-2- yl] ureas have been accomplished by condensation of equimolar quantities of chlorides of various carbamidophosphoric acids (3) with 3-hydroxyl-6-methyl-2-pyridinemethanol (lutidine diol)(4) in the presence of triethylamine in dry toluene–tetrahydrofuran (1: 1) mixture at 45–50 C. Their structures were established by elemental analyses, IR, 1 H NMR, 13 C ...