Copper-promoted N-cyclopropylation of anilines and amines by cyclopropylboronic acid
S Bénard, L Neuville, J Zhu
Index: Benard, Sebastien; Neuville, Luc; Zhu, Jieping Chemical Communications, 2010 , vol. 46, # 19 p. 3393 - 3395
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Citation Number: 21
Abstract
Reaction of anilines, primary and secondary aliphatic amines with cyclopropylboronic acid in dichloroethane in the presence of Cu (OAc) 2 (1 equiv.), 2, 2′-bipyridine (1 equiv.) and sodium carbonate or sodium bicarbonate (2 equiv.) under air atmosphere afforded the corresponding N-cyclopropyl derivatives in good to excellent yields.
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