Novel and Convenient Routes to Functionalized Alkynyl Ketones from 1-(Benzotriazol-1-yl) propargyl Ethyl Ethers
AR Katritzky, H Lang
Index: Katritzky, Alan R.; Lang, Hengyuan Journal of Organic Chemistry, 1995 , vol. 60, # 23 p. 7612 - 7618
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Citation Number: 58
Abstract
1-(Benzotriazol-1-yllpropargyl ethyl ethers, readily accessible from propargyl aldehyde diethyl acetals and benzotriazole, undergo smooth lithiation at the methine carbon and subsequent reactions with alkyl halides, aldehydes, ketones, imines, esters, trialkylsilyl chlorides, dialkyl carbonates, and isocyanates to yield the corresponding substituted ethers. Hydrolysis of these intermediates under acidic conditions affords a wide variety of alkynyl ...
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