Exo-Selective Diels-Alder Reaction Based on a Molecular Recognition Approach

K Maruoka, H Imoto, H Yamamoto

Index: Maruoka, Keiji; Imoto, Hiroshi; Yamamoto, Hisashi Journal of the American Chemical Society, 1994 , vol. 116, # 26 p. 12115 - 12116

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Citation Number: 63

Abstract

The Diels-Alder reaction and its variants (inverse-electron demand and hetero) offer many synthetic advantages in terms of simplicity and versatility, as exemplified by their broad application to the stereo-and regiochemically defined synthesis of a wide variety of natural products.'In particular, the use of Lewis acid catalysis in these cycloadditions allows rigorous creation of four contiguous stereocenters with largely predictable regio-and ...