Research on Chemical Intermediates

Synthetic and mechanistic investigation of piperonyl butoxide from dihydrosafrole

S Wang, J Liu, C Qian, X Chen

Index: Wang, Shuai; Liu, Jinqiang; Qian, Chao; Chen, Xinzhi Research on Chemical Intermediates, 2012 , vol. 38, # 1 p. 147 - 160

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Abstract

Abstract Piperonyl butoxide (PBO) 1 was prepared via the successive chloromethylation and etherification of dihydrosafrole 3. In this work, during the chloromethylation of 3, several by- products such as 5 (the isomer of chloromethyldihydrosafrole 4), 6-propylpiperonyl alcohol 6, bis (chloromethyl)-dihydrosafrole 7 and 8, bis (2-propyl-4, 5-methylenedioxyphenyl) methane 9 and di (2-propyl-4, 5-methy lene-dioxybenzyl) ether 10 were found. However, it ...