Journal of the American Chemical Society

One-electron vs. two-electron oxidations. Vanadium (V) oxidation of cyclobutanols

J Rocek, DE Aylward

Index: Rocek,J.; Aylward,D.E. Journal of the American Chemical Society, 1975 , vol. 97, p. 5452 - 5456

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Citation Number: 40

Abstract

Abstract: Vanadium (V) in aqueous perchloric acid oxidized 2-ethylcyclobutanols and 2, 2- dimethylcyclobutanol to 4-hydroxyhexanal and 4-hydroxy-4-methylpentana1, respectively. In Hzl* O cyclobutanol gives 4-hydroxybutanol with I8O incorporated in the hydroxyl group. The oxidation of the cyclobutanols follows the rate law u= k [V (V)][ROHIho, with the relative reactivities for cyclobutanol, 2-ethylcyclobutanol, and 2, 2-dimethylcyclobutanol being 1. O ...

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