A Highly Diastereomerically Enriched, Silyl??Substituted Alkyl Lithium, Configurationally Stable at Room Temperature

C Strohmann, BC Abele, K Lehmen…

Index: Strohmann, Carsten; Abele, Bors C.; Lehmen, Klaus; Schildbach, Daniel Angewandte Chemie - International Edition, 2005 , vol. 44, # 20 p. 3136 - 3139

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Citation Number: 26

Abstract

Over the last 20 years, a number of enantiomerically and diastereomerically enriched [1] alkyl lithium compounds have been reported.[2, 3] For most of the compounds the configuration of the metalated stereogenic carbon center is only stable at low temperatures (À788C). However, more recently, corresponding compounds have been synthesized which have proved to be configurationally stable for a few minutes at higher temperatures, ...