Quinone alkylation using organocadmium reagents: a general synthesis of quinols

A Aponick, JD McKinley, JC Raber…

Index: Aponick, Aaron; McKinley, Jason D.; Raber, Jeffrey C.; Wigal, Carl T. Journal of Organic Chemistry, 1998 , vol. 63, # 8 p. 2676 - 2678

Full Text: HTML

Citation Number: 15

Abstract

Reactions of p-benzoquinone with organocadmium reagents yield quinols, the result of quinone carbonyl monoalkylation. The reactions proceed in good yield and are devoid of bisaddition and hydroquinone byproducts. Quinone alkylations using this method show general applicability to p-benzoquinone as well as extended quinone systems using primary alkyl, secondary alkyl, and aryl reagents.

Related Articles:

The transannular ozonide of 9-tert-butyl-10-methylanthracene

[Ito,Y.; Matsuura,A.; Otani,R. Journal of the American Chemical Society, 1983 , vol. 105, p. 5699]

Elucidation of the electron transfer reduction mechanism of anthracene endoperoxides

[Donkers, Robert L.; Workentin, Mark S. Journal of the American Chemical Society, 2004 , vol. 126, # 6 p. 1688 - 1698]

Tandem directed metalation reactions. Short syntheses of polycyclic aromatic hydrocarbons and ellipticine alkaloids

[Watanabe; Snieckus Journal of the American Chemical Society, 1980 , vol. 102, # 4 p. 1457 - 1460]

A novel [1, 2] alkyl shift in a blocked aromatic anion

[Miller, Bernard; Bhattacharya, Ajit K. Journal of the American Chemical Society, 1980 , vol. 102, # 7 p. 2450 - 2451]

A novel [1, 2] alkyl shift in a blocked aromatic anion

[Miller, Bernard; Bhattacharya, Ajit K. Journal of the American Chemical Society, 1980 , vol. 102, # 7 p. 2450 - 2451]

More Articles...