The Journal of Organic Chemistry

Azetidines. II. Synthesis and Stevens rearrangement of 2-phenyl-1, 1, 3, 3-tetramethylazetidinium iodide

AG Anderson Jr, MT Wills

Index: Anderson,A.G.; Wills,M.T. Journal of Organic Chemistry, 1968 , vol. 33, # 2 p. 536 - 541

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Citation Number: 4

Abstract

The title compound (2) was synthesized by two routes. l-Chloro-2, 2-dimethyl-3- dimethylamino-l-phenyl-propane (5), prepared from 2, 2-dimethyl-3-dimethylaminopropanol (3) via 2, 2-dimethyl-3-dimethylamino-1-phenyl-1-propanol (4 j, gave 2 when treated with sodium iodide. Methyl-3-bromo-2, 2-dimethyl-3-phenylpropyl-ammonium bromide (8) was obtained from the benzamide (9) of 2, 2-dimethyl-3-methylaminopropanal (6) via 2, 2- ...